Techniques to stop negative thoughts. Before treating headaches in patients not previously diagnosed with migraine or cluster headache or in patients who present with atypical symptoms, exclude other potentially serious neurological conditions. Imitrex Injection is contraindicated in patients with a history of stroke or TIA. Who should not take Imitrex?
If you are not sure if you have these types of migraines, ask your healthcare provider. Nursing Mothers: Sumatriptan is excreted in human breast milk. Therefore, caution should be exercised when considering the administration of IMITREX Injection to a nursing woman. Rare were herpes, swelling of face, sweating, and peeling of skin. HT 1 agonists. Since visual disorders may be part of a migraine attack, a causal relationship between these events and the use of 5-HT 1 agonists have not been clearly established.
Dose selection for the older patient should be cautious, generally starting at the lower end of the dosing range due to a greater frequency of hepatic, renal, cardiac impairment as well as presence of concomitant disease or drug therapy. IMITREX and AMERGE are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products. Patients who are advised to self-administer IMITREX Injection in medically unsupervised situations should receive instruction on the proper use of the product from the physician or other suitably qualified health care professional prior to doing so for the first time.
Throw away the seal. Open the lid over the Syringe Cartridge. Imitrex Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection. You may experience pain or redness at the site of injection, but this usually lasts less than an hour. TIA. Discontinue Imitrex Tablets if a cerebrovascular event occurs.
Dogs receiving oral sumatriptan developed corneal opacities and defects in the corneal epithelium. Reduce your stress. Being anxious can impair your memory. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice. If you get headaches often, talk to your doctor about whether you need a medication to help prevent them. This medication may interfere with certain laboratory tests including bleeding times, adrenal function tests possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Neurological: Infrequent were mental confusion, euphoria, agitation, relaxation, chills, sensation of lightness, tremor, shivering, disturbances of taste, prickling sensations, paresthesia, stinging sensations, facial pain, photophobia, and lacrimation. Your healthcare provider may change your dose. Do not change your dose without first talking to your healthcare provider. If migraine returns after an initial dose of subcutaneous injection, additional oral doses may be given up to 100 mg orally per day, with at least a 2 hour interval between tablet doses. Ways to manage your time. They may have fewer side effects than prescription drugs. All medicines may cause side effects, but many people have no, or minor, side effects. Treatment for these health problems also may help you have fewer headaches. If you are taking a liquid product, use a medication-measuring device to carefully measure the dose. Do not use a household spoon. Some liquid products need to be shaken before each dose. Some products that contain need to be placed under the and held there before swallowing. Follow label directions carefully to get the most benefit. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. Imitrex, IMITREX STATdose Pen, and IMITREX STATdose System are registered trademarks of the GSK group of companies.
Because it sure FEELS serious! Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Read this Patient Information before you start taking Imitrex and each time you get a refill. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or treatment. Researchers say triptans have become extremely popular in migraine treatment since they were introduced a decade ago. But many doctors do not understand why the drugs work well in some patients and not at all in others and why their effectiveness varies in individual patients from one migraine attack to the next. The trials did not establish the efficacy of Imitrex Nasal Spray compared with placebo in the treatment of migraine in adolescents. Adverse reactions observed in these clinical trials were similar in nature to those reported in clinical trials in adults. Following subcutaneous administration of sumatriptan, pain, redness, stinging, induration, swelling, contusion, subcutaneous bleeding, and, on rare occasions, lipoatrophy depression in the skin or lipohypertrophy enlargement or thickening of tissue have been reported. Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw commonly occur after treatment with Imitrex Tablets and are usually non-cardiac in origin. However, perform a cardiac evaluation if these patients are at high cardiac risk. Oral treatment of pregnant rats with sumatriptan during the latter part of gestation and throughout lactation resulted in a decrease in pup survival. Store Imitrex spray between 36 and 86 degrees F 2 and 30 degrees C. Store away from heat, moisture, and light. Do not freeze. Do not store at temperatures above 86 degrees F 30 degrees C. Do not store in the bathroom. Keep Imitrex spray in the case provided. Throw away expired medicine as directed by your doctor the expiration date is printed on the treatment pack. Keep Imitrex spray out of the reach of children and away from pets. What are the ingredients in Imitrex Injection? It is not known if Imitrex is safe and effective to treat cluster headaches. An extra patient leaflet is available with Imitrex tablets. Talk to your pharmacist if you have questions about this information. System out of the reach of children. Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred in patients treated with 5-HT 1 agonists, and some have resulted in fatalities. In a number of cases, it appears possible that the cerebrovascular events were primary, the 5-HT 1 agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migraine when they were not. CAD prior to receiving Imitrex Tablets. If there is evidence of CAD or coronary artery vasospasm, Imitrex Tablets are contraindicated. For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of Imitrex Tablets in a medically supervised setting and performing an electrocardiogram ECG immediately following administration of Imitrex Tablets. For such patients, consider periodic cardiovascular evaluation in intermittent long-term users of Imitrex Tablets. If you are taking chewable tablets, chew the tablet thoroughly before swallowing. fluticasone
Injection in pregnant women. Renal Impairment: The effect of renal impairment on the pharmacokinetics of sumatriptan has not been examined. Spierings EL "Intracranial hemorrhages associated with sumatriptan. In vitro studies with human microsomes suggest that sumatriptan is metabolized by MAO, predominantly the A isoenzyme. Most of a radiolabeled dose of sumatriptan excreted in the urine is the major metabolite indole acetic acid IAA or the IAA glucuronide, both of which are inactive. If you also take any ergotamine medication such as dihydroergotamine or other "triptan" drugs such as zolmitriptan, rizatriptan you will need to separate your sumatriptan dose from your dose of these other medications to lessen the chance of serious side effects. Ask your doctor how long you should wait between your doses of these drugs. ranolazine place to buy ranolazine
It may harm them. Overall, the frequency of adverse reactions reported in the trials of cluster headache was generally lower than in the migraine trials. Exceptions include reports of paresthesia 5% Imitrex Injection, 0% placebo nausea and vomiting 4% Imitrex Injection, 0% placebo and bronchospasm 1% Imitrex Injection, 0% placebo. After using one nasal capsule in each nostril: If your headache does not completely go away, or goes away and comes back, you may use a second dose 1 capsule per nostril if it has been at least two hours since you used the first capsules. Do not use more than two doses 4 nosepieces in 24 hours. If your symptoms do not improve, contact your doctor before using any more sumatriptan nasal capsules. Trials 1, 2, and 3 following administration of Imitrex Tablets compared with placebo. After taking a sumatriptan tablet, you must wait two 2 hours before taking a second tablet. Do not take more than 200 mg of sumatriptan tablets in 24 hours. IMITREX STAT dose System NDC 0173-0739-02. Ottervanger JP, Vanwitsen TB, Valkenburg HA, Grobbee DE, Stricker BHC "Adverse reactions attributed to sumatriptan - a postmarketing study in general practice. Case to reset the white Priming before the next use. Remove STAT dose Pen from s kin. Complete the What is a document? Eye: Accommodation disorders, blindness and low vision, conjunctivitis, disorders of sclera, external ocular muscle disorders, eye edema and swelling, eye hemorrhage, eye itching, eye pain, keratitis, mydriasis, and visual disturbances. Single doses of 5, 10, or 20 mg of Imitrex Nasal Spray administered into 1 nostril were effective for the acute treatment of migraine in adults. These trials did not establish the efficacy of oral Imitrex compared with placebo in the treatment of migraine in adolescents. Adverse reactions observed in these clinical trials were similar in nature to those reported in clinical trials in adults. My diarrhea came as the result of returning to eating more "normal" food, after being on the "Very Low Calorie Diet" VLCD phase of the hcg diet. I'm not talking about suddenly eating at Taco Bell. There were insufficient data to assess the impact of race on efficacy. Other Events Observed in Association With the Administration of IMITREX Injection: In the paragraphs that follow, the frequencies of less commonly reported adverse clinical events are presented. Because the reports include events observed in open and uncontrolled studies, the role of IMITREX Injection in their causation cannot be reliably determined. Furthermore, variability associated with adverse event reporting, the terminology used to describe adverse events, etc.
The osmolality of both injections is 291 mOsmol. Preventive medicines often work when you take them at the first sign of a new cluster of headaches. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. This may not be a complete list of all interactions that may occur. Ask your health care provider if Imitrex tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. Anti-nausea medications. These drugs may help you absorb your pain medication. Overuse of Imitrex tablets can cause your headache to become worse. Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor. Ear, Nose, and Throat: Deafness. After a better Tuesday, the diarrhea returned on Wednesday. Do not use sumatriptan if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Urogenital: Rare were dysuria, frequency, dysmenorrhea, and renal calculus. cheap zithromax online overnight shipping zithromax
Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Do not take more than the amount prescribed by your doctor in a 24-hour period or treat more than 4 headaches within 30 days without checking with your doctor. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case. The Pen is used to automatically inject 1 dose of medicine from a Syringe Cartridge. IMITREX is working for you. duloxetine ointment brand name
Refill Cartridge Packs are available. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Musculoskeletal: Infrequent were various joint disturbances pain, stiffness, swelling, ache. Rare were muscle stiffness, need to flex calf muscles, backache, muscle tiredness, and swelling of the extremities. Write your daily activities on a calendar or daily planner, and keep it in a place where you can see it easily. Avoid for at least 12 hours after using sumatriptan. Consult your doctor before -feeding. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. See Drug Reference for a full list of side effects. Drug Reference is not available in all systems. Check your pressure regularly and tell your doctor if the results are high. They are usually triggered after pain medicine has worn off, prompting you to take another dose. Eventually you get a headache whenever you stop taking the drug. Be sure to take your migraine medicine only as prescribed by your doctor. This year, I finally went to a doctor because I was tired of my migraines controlling my life. She first gave me the sumatriptan pills 10 mg at first, then 20 mg but it didn't stop the vomiting. Therefore, I couldn't keep the medicine down long enough for it to start working. So, she prescribed me the nasal spray. This drug may rarely cause serious possibly fatal disease. Meniere disease; nasal inflammation; otalgia; sensitivity to noise; sinusitis; tinnitus; and upper respiratory inflammation.
Check the expiration date on the Cartridge Pack. F. Protect from light. You don't want to take your medicine too often, since it may stop working or cause more intense and more frequent "rebound headaches. The Pen is now ready to use. This medication should be taken only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. For women, at what time in your monthly cycle do they happen? Not all side effects for Imitrex may be reported. You should always consult a doctor or healthcare professional for medical advice. Because IMITREX Injection may increase blood pressure, it should not be given to patients with uncontrolled hypertension. Loss of vision included reports of permanent defects. Causality has not been established as visual disorders may occur during a migraine attack itself. Incidence in Controlled Trials of Cluster Headache: In the controlled clinical trials assessing sumatriptan's efficacy as a treatment for cluster headache, no new significant adverse events associated with the use of sumatriptan were detected that had not already been identified in association with the drug's use in migraine. The use of Imitrex Tablets is contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Imitrex Tablets. Some of these reactions occurred in patients without known CAD. generic azulfidine money order store
Corneal Opacities: Sumatriptan causes corneal opacities and defects in the corneal epithelium in dogs; this raises the possibility that these changes may occur in humans. This product passes into milk. While there have been no reports of harm to nursing infants, consult your doctor before -feeding. Overall, the frequency of adverse events reported in the studies of cluster headache were generally lower. Exceptions include reports of paresthesia 5% IMITREX, 0% placebo nausea and vomiting 4% IMITREX, 0% placebo and bronchospasm 1% IMITREX, 0% placebo. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Some people may have feelings of tingling, heat, flushing redness of face lasting a short time heaviness or pressure after treatment with IMITREX Injection. A few people may feel drowsy, dizzy, tired, or sick. Tell your doctor of these symptoms at your next visit. Chiari M, Manzoni GC, Vandegeijn EJ "Ischemic optic neuropathy after sumatriptan in a migraine with aura patient. IMITREX STATdose Pen. Visually inspect the vial for particulate matter and discoloration before administration. Do not use if particulates and discolorations are noted. Eye: Infrequent were irritation of eyes and visual disturbance. It is unknown if this drug passes into milk. Consult your doctor before -feeding. IMITREX. Such reactions can be life threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Imitrex Injection is contraindicated in patients with a history of hypersensitivity reaction to IMITREX. efil.info albenza
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Product Information. Alsuma SUMAtriptan. The treatment of migraine headaches with or without aura eg, flashing lights, wavy lines, dark spots. It may also be used for other conditions as determined by your doctor. Mueller L, Gallagher RM, Ciervo CA "Vasospasm-induced myocardial infarction with sumatriptan. carafate in pharmacy
Some of the side effects that can occur with sumatriptan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. How often do you have them? You should not use this medicine if you have uncontrolled high blood pressure, heart problems, certain heart rhythm disorders, a history of heart attack or stroke, or circulation problems that cause a lack of blood supply within the body.
If you have a higher risk for heart problems see Precautions your doctor may perform a heart exam before you start taking sumatriptan. US Food and Drug Administration "FDA Drug Safety Communication: FDA evaluating the risk of burns and scars with Zecuity sumatriptan migraine patch. IMITREX. Such reactions can be life threatening or fatal. oxybutynin
IMITREX Injection should not be given to patients with history, symptoms, or signs of ischemic cardiac, cerebrovascular, or peripheral vascular syndromes. In addition, patients with other significant underlying cardiovascular diseases should not receive IMITREX Injection. The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions.